This course explores the fundamentals of environmental health, giving students a solid grounding in current issues and controversies and enhancing understanding of the scientific data that drives these issues. It includes readings that illustrate concepts in the context of a developed country, as well as readings that illustrate that same concept in a developing country. By examining environmental health from local to regional perspectives, the materials also educate students about a variety of environmental health topics including human population, toxicology/biomes, water resources, solid and hazardous waste management, environmental justice, communications, technology, regulatory policy, and the consequences of human activity on natural systems. Some of these issues are further addressed with hands-on experiences in field trips. Though this course, we aim to lay out the facts, make the connections, and demonstrate the importance of crucial environmental health issues to human health and well-being, both in our homes, workplaces, and neighborhoods, and on a global scale.