The aim of this course is to introduce concepts of study design, data collection, and statistical analysis commonly used in public health research with a focus on the application in public health practice. This course includes three parts: The first part is “study design”, which gives an introduction of causal inference and the principle of study design. The second part is “analytical method”, which gives an introduction on data analyses and the applications of statistical method. The third part is critical appraisal of public health literatures. Examples from Taiwan unique research topics are given and illustrated in the course. For lab data analyses, some example datasets will be provided to students. Students will perform statistical analyses using these datasets. We will mainly use R program for class discussion. For lab data analyses, some example datasets will be provided to students. Students will perform statistical analyses using these datasets. We will mainly use R program for class discussion. The TA will demonstrate the R code and provide the answers for specific topics.